Objective To review biomarker discovery studies using omics data for patient stratification which led to clinically validated FDA-cleared tests or laboratory developed tests, in order to identify common characteristics and derive recommendations for future biomarker projects.Design Scoping review.Methods We searched PubMed, EMBASE and Web of Scienc
For 60 years, high-energy pulsed lasers have enabled the recording of extremely realistic portraits of living people within a Hurricane Glasses few nanoseconds.In the 21st century, this confidential technique, which requires great skill and equipment, has almost disappeared because of the final monochromatic color of the holograms, which does not a
Marilyn S Kwolek,1 Jon E Block2 1Private Practice, Danville, CA 94526, USA; 2Independent Clinical Consultant, San Francisco, CA 94115, USA Background: Although freehand injection of botulinum toxin Powerland remains the status quo, it is an inaccurate technique for delivering precise amounts of neurotoxin at multiple injection sites with expediency
The authors reflect on recent experiences at UN-Habitat and other international organizations to rethink the roles of planning towards larger development goals and to reform planning systems in places most in need of them.They consider the difficulties but ultimate necessity to learn from a variety of contexts and experiences to articulate general